研究方向：
1.结核病的分子流行病学:
2.结核分枝杆菌高致病菌株的起源与致病性演化:
3.结核分枝杆菌耐药新基因的发现与分子机制
科研项目：
2017，国家自然科学基金-盖茨基金会国际合作项目，“利用生物标志物预测可短程治愈结核病患者的研究”，主持
2017，国家自然科学基金重大研究计划集成项目，“结核分枝杆菌优势亚型的高致病性进化机制研究”，主持
2017，国家传染病重大专项，“以患者发现为主的结核病干预策略研究”，子课题负责人
2019，国家自然科学基金面上项目，“分枝杆菌CpsA蛋白的功能及其致病的分子机制研究”，主持
代表性论著：
1. Liu Q,
Liu H，Shi L, Gan M, Zhao X, Lyu L, Takiffe H, Wan K and Gao
Q，Local adaptation of Mycobacterium tuberculosis on the
Tibetan Plateau，PNAS 2021，Vol. 118 No. 17 e2017831118，https://doi.org/10.1073/pnas.2017831118
2. Luo T,
Xu P, Zhang Y, Porter J, Ghanem M , Liu Q, Jiang Y, Li J, Miao Q, Hu B, Howden B,
Fyfe J, Globan M, He W, He P, Wang Y, Liu H, Takiff H, Zhao Y, Chen X, Pan Q,
Behr M, Stinear T, Gao Q，Population genomics provides insights
into the evolution and adaptation to humans of the waterborne pathogen
Mycobacterium kansasii，NATURE COMMUNICATIONS | (2021)12:2491 | https://doi.org/10.1038/s41467-021-22760-6J
3. Liu Q,
Wei J, Li Y, Wang M, Su J, Lu Y, López
M, Qian X, Zhu Z, Wang H, Gan M, Jiang Q,Fu Y, Takiff H, Comas I, Li F, Lu X, Fortune S, Gao Q. Mycobacterium
tuberculosis clinical isolates carry mutational signatures of host immune
environments. SCIENCE ADVANCES. 2020; 6 : eaba4901. 29 May 2020
4. Liu
Q, Ma A, Wei L, Pang Y, Wu B, Luo T, Zhou Y, Zheng H, Jiang Q, Gan M, Zuo T,
Liu M, Yang C, Jin L, Comas I, Gagneux S, Zhao Y, Pepperell CS, Gao Q.
China's tuberculosis epidemic stems from historical expansion of four strains
of Mycobacterium tuberculosis. Nat Ecol Evol. 2018
Dec;2(12):1982-1992.
5. Yang
C., Luo T, Shen X, Wu J, Gan M, Xu P, Wu Z, Lin S, Tian J, Liu Q, Yuan Z, Mei
J, K. DeRiemer, Gao Q. Transmission of multidrug-resistant Mycobacterium
tuberculosis in Shanghai, China: a retrospective observational study using
whole-genome sequencing and epidemiological investigation. Lancet
Infectious Diseases 2017 Mar 17(3): 275-284.